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Akali Rune for Mid, Emerald +Patch 13.23
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Let the data do the talking: these are the best runes by win rate for Akali Mid vs All Champions. U.GG takes the guesswork out of Akali runes. LoL Patch 13.23
Let the data do the talking: these are the best runes by win rate for Akali Mid vs All Champions. U.GG takes the guesswork out of Akali runes. LoL Patch 13.23
Pro BuildsFilters
Middle
Emerald +Ranked Solo
Filters
Middle
Emerald +Ranked Solo
Best Akali Runes
49.6% WR (21,747 Matches)
Domination
Resolve
Domination
Resolve
At 49.6% winrate over 21,747 matches, this specific Mid Akali rune page has worked the best for most players in Emerald + vs
All Champions
.
Akali benefits from the stacking damage stats from 
Eyeball Collection.
Take 
Overgrowth to increase your HP as the game goes on.
Stat Shards
Take Adaptive Force (1), Adaptive Force (2), and Armor (3) on Akali Mid vs All Champions. Shards should be based on matchup.
1. First slot Adaptive Force grants strong early damage potential and burst for Akali Mid.
2. Adaptive Force is the standard second shard into most matchups.
3. Take Armor third versus physical damage (AD) matchups.